| 학회 |
한국공업화학회 |
| 학술대회 |
2011년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터) |
| 권호 |
15권 1호 |
| 발표분야 |
나노 |
| 제목 |
Fabrication of Nano-scale Liposomes via SPG Membrane for Drug Delivery |
| 초록 |
Doxorubicin (DOX)-loaded liposomes were prepared using Shirasu porous glass (SPG) membranes with different pore sizes for cancer chemotherapy. Primary liposomes were prepared by film-hydration method and then using SPG membranes for size control. Morphology and size of liposomes were confirmed using the optical microscope and dynamic light scattering. The small pore size and higher applied pressure resulted in the liposomes with smaller size. After preparing liposomes, DOX was loaded into the liposomes by remote loading method. The release amount of DOX of DOX-loaded liposomes was measured by UV-vis spectrophotometer. |
| 저자 |
황태원1, 박태준1, 고원건1, 정인우2, 최성욱3, 김중현1
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| 소속 |
1연세대, 2경북대, 3카톨릭대 |
| 키워드 |
Liposomes; Shirasu porous glass membrane; Membrane emulsification; Pressure
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| E-Mail |
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