| 초록 |
Cysteine is an essential amino acid. It plays considerably important role of binding motifs in biological systems such as zinc fingers, coenzyme A, and glutathione. Furthermore, reversible oxidation–reduction reaction of cysteine is an essential process in substantial number of biological systems. This strong oxidation–reduction activity was mainly driven from the thiol group. In this study, a novel biomimetic bolaamphiphilic molecule containing cysteinyl group at both ends was synthesized through conjugation of alkyl chain with cysteine. The newly synthesized bolaamphiphilic molecule self-assembled in the pH-controlled aqueous solution, and display well-ordered structure. Structure of the molecule and the mechanism of the self-assembly were investigated through microscopic and spectroscopic methods. The cysteinyl bolaamphiphile constructed microtubular structures showing enhanced affinity to the metal ions, and this superstructure was exploited to produce inorganic-organic hybrid materials exploiting the reducing property of the thiol moiety. |
