화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2019년 가을 (10/30 ~ 11/01, 제주국제컨벤션센터(ICC JEJU))
권호 23권 2호
발표분야 포스터_콜로이드·계면화학
제목 Surface Functionalized-Polydopamine Nanoparticles by Diamine Molecules for Biological Imaging
초록 Novel fluorescent nanoparticles have consistently attracted a great research interest due to their superior optical characteristic and inter cellular targetting. A prospective nanoprobe should have a suitable size and size distribution, high water dispersibility, good biocompatibility and biodegradability. Although FINs possess remarkable fluorescence properties and have been widely explored for bioimaging applications, most of the FINs are non-biodegradable, in addition, some of them have shown a fatal toxicity to living organisms. In this work, we reported that novel fluorescent polydopamine nanoparticles (FPNPs) can be conveniently fabricated via the diamine molecules-induced degradation of as-prepared non-fluorescent polydopamine (PDA) microparticles at room temperature. The FPNPs exhibited strong green fluorescence, high water solubility and good biocompatibility, fabricating them highly potential for biological imaging application.
저자 박철순1, 배준원2, 권오석1
소속 1한국생명공학(연), 2동덕여자대
키워드 polydopamine; surface functionalization; in-vitro and in-vivo imaging
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