초록 |
Novel fluorescent nanoparticles have consistently attracted a great research interest due to their superior optical characteristic and inter cellular targetting. A prospective nanoprobe should have a suitable size and size distribution, high water dispersibility, good biocompatibility and biodegradability. Although FINs possess remarkable fluorescence properties and have been widely explored for bioimaging applications, most of the FINs are non-biodegradable, in addition, some of them have shown a fatal toxicity to living organisms. In this work, we reported that novel fluorescent polydopamine nanoparticles (FPNPs) can be conveniently fabricated via the diamine molecules-induced degradation of as-prepared non-fluorescent polydopamine (PDA) microparticles at room temperature. The FPNPs exhibited strong green fluorescence, high water solubility and good biocompatibility, fabricating them highly potential for biological imaging application. |