| 학회 |
한국고분자학회 |
| 학술대회 |
2014년 봄 (04/10 ~ 04/11, 대전 컨벤션센터) |
| 권호 |
39권 1호 |
| 발표분야 |
Functional Colloids for Dermatology |
| 제목 |
Biomimetic and Lyotropic Liquid Crystal Emulsions for Cosmetic Appliucations |
| 초록 |
Human stratum corneum (hSC) is consisted of several layers of corneocytes embedded in a lipid mixture of ordered lamellar structure. The lipid-rich and well-ordered intercellular regions in the hSC are the continuous domains and these domains play a important role in the skin barrier function. In this study, we prepared liquid crystal emulsions (LCEs) which are expected to improve the skin barrier function and skin penetration of cosmetic active ingredients due to their multi-lamellar structures which are similar to the structure and formulations of hSC. The LCEs were incorporated with amphiphilic molecules in an optimized manufacturing process and identified with polarized light microscopy, X-ray diffraction analysis, cryo-electron microscopy and Mueller matrix method. In skin penetration experiments, we found the LCEs shows higher flux values of the ingredients compared with that of the general emulsions without lamellar liquid crystal phase. |
| 저자 |
이준배1, 이동렬2, 예하늬3, 전성운3, 김범종3, 김영희4, 박천호1, 장지희1, 홍성규3, 유혁상4, 윤명석1, 김병문2, 김한곤1
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| 소속 |
1코스맥스(주), 2서울대, 3동국대, 4강원대 |
| 키워드 |
Biomimetic; Lyotropic; Liquid Crystal
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| E-Mail |
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