초록 |
The formation of CFNs ranked according to size was predicted well and explained reasonably by the criterion, considering both the ionic strength of the entrapped solution in CFNs and the nonspecific binding (interaction) of the positive amino groups among the chitosan molecules. Furthermore, the fraction of nonspecifically-bound positive amino groups was quantified from the positive net charged amino groups per unit-mass CFN. Thus, its magnitude was predicted to have a strong correlation with the CFN-preparation conditions, such as pH and FCMRs. Using the model predicted size of CFNs, zeta potential can be predicted in terms of pH and FCMRs. |