화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터)
권호 14권 2호
발표분야 생물공학
제목 Preparation of Caffeoyl Proline Hydroxamic acid Metal Complex and Its Biological Activity
초록 Developing anti-aging and depigmentating agents have been important subjects of cosmeticindustry. In our previous study, we found that caffeoylprolinehydroxamic acid showed a strong antioxidant activity and tyrosinase inhibitory activity. However, this compound is too hydrophilic to exert its biological activity in the cell, thus we prepared its metal complex to enhance its cell permeability by increasing lipophilicity. We will discuss about their biological activities in the cell.
저자 이송, 곽선영, 이윤식
소속 서울대
키워드 hydroxamic acid; metal complex; cell permeability
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