| 학회 |
한국공업화학회 |
| 학술대회 |
2010년 가을 (10/27 ~ 10/29, 대전컨벤션센터) |
| 권호 |
14권 2호 |
| 발표분야 |
차세대 스텐트 소재 |
| 제목 |
Synthesis and Mucoadhesive Properties of Catechol-Containing Polymers |
| 초록 |
We report on the synthesis of the mucoadhesive polymers for covering materials of non-vascular stents. The polymers were designed to have catechol groups, which are the main components of mussel adhesive proteins. The polymers displayed the good adhesion properties in the presence of small amounts of oxidants. The mucoadhesion properties of the polymers were examined using small intestinal submucosa (SIS). The adhesive strength of the catechol-containing polymers was much higher than the currently used fibrin glue. The adhesive polymers exhibited the mucoadhesion strength of 1.2 MPa, as compared with 0.52 MPa of the fibrin glue. The catechol-containing polymers can be used as a coating material for the adhesive non-vascular stents. |
| 저자 |
이상천 |
| 소속 |
경희대 |
| 키워드 |
mucoadhesion; catechol; mussel; stent
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| E-Mail |
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