| 초록 |
We investigated a novel fluorescent sensor based on the molecular imprinting technique. A mesoporous silica particle was used as an imprinting material and a CdSe quantum dot (QD) as a signal transducer. Bisphenol-A (BPA) was adopted as a template molecule, which is known as an endocrine disrupting chemical. Binding sites were uniformly formed between the pores and CdSe QDs were introduced inside the pores of the mesoporous silica. QD-encapsulated, molecularly imprinted mesoporous silica (QD-MIMS) achieved outstanding molecular recognition properties in respect of sensitivity and selectivity. Due to close proximity of the binding sites to the QDs, a notable fluorescence quenching of QD was exhibited in the presence of BPA. Stern-Volmer equation was used to model the fluorescence quenching behavior of QD-MIMS. QD-MIMS showed that the quenching constant for BPA is nearly 10 times larger than that for its structural analogs, verifying a noteworthy selectivity of QD-MIMS toward BPA. |
