| 초록 |
Hydrogels that are responsive to external stimulation have become increasingly popular in recent years for simple, rapid and precise drug delivery that can be controlled by simply switching the external stimulus on or off. This study investigated electrical and thermal-responsive hydrogels based on pristine carbon nanotubes as the electrical/thermal conductor and core unit, chitosan as a natural glue and shell unit, and poly(NIPAAm-co-BBVIm) as a temperature-responsive copolymer and drug carrier. Uniform distribution and 3D connectivity of CNTs was improved by formulating the CNT-core and Chit-shell units and constructing a CNT sponge framework. The physiochemical, mechanical, electrical, thermal, and biocompatibility characteristics of the 3D framed hydrogel led to remarkable electrical- and thermal-responsive properties that allowed for the development of an excellent controllable and switchable drug delivery platform. |
