| 학회 | 한국화학공학회 |
| 학술대회 | 2007년 가을 (10/26 ~ 10/27, 한국과학기술원) |
| 권호 | 13권 2호, p.1728 |
| 발표분야 | 생물화공 |
| 제목 | Fabrication of cancer cell chip using modified RGD peptide |
| 초록 | Most of the common materials have sufficient mechanical stability and elasticity as well as desired stability towards degradation, and are non-toxic. One important problem is inadequate interaction between metal and cells. Metals usually don’t show biocompatibility, therefore we try to make a condition to cells using peptides. We used 3 kinds of peptide which is CRGD, CRGD-MAP, RGD-MAP-C, and immobilize it on the gold plate. We confirmed the peptide with AFM and growing the cells on the peptide modified surface. The cells’ growing pattern and the relation with peptide pattern could be the new approach to the substrate modification technology to apply to the cell chip that can detect the cells by electrical or electrochemical mehods. Acknowledgments : This research was supported by Seoul R&BD Program(10816) and by the Nano/Bio Science & Technology Program (2006-00955) of the Ministry of Science and Technology, supported by the Korea government(MOST) (2006-05374). |
| 저자 | 예철헌1, 김현희1, 이진호1, 민준홍2, 최정우1 |
| 소속 | 1서강대, 2경원대 |
| 키워드 | cell chip; immobilization; bioplatform; peptide |
| 원문파일 | 초록 보기 |
