| 학회 |
한국공업화학회 |
| 학술대회 |
2012년 가을 (10/31 ~ 11/02, 대전컨벤션센터) |
| 권호 |
16권 2호 |
| 발표분야 |
포스터-정밀화학 |
| 제목 |
Analysis of Rapamycin-Eluting Stent coated biodegrable polymer |
| 초록 |
Coronary arterial stenting with drug-eluting stent (DES) is a major therapy for the treatment of coronary arterial diseases inpresent interventional cardiology practice. Rapamycin (also called sirolimus) is a macrocyclic lactone drug approved by FDA. In vitro and in vivo studies indicate that it can significantly prevent proliferation of vascular smooth muscle cell of human and inhibit in-stent restenosis due to neointima formation. Rapamycin also has anti-inflammatory activity. So, the rapamycin-eluting stents were extensively studied by many people and many meaningful results were obtained. In this study, Rapamycin-elutiong metal stent were prepared through an nano spray-coating method. DES(drug-eluting stent) composed of biodegradable poly(ε-Caprolactone) and rapamycin. The study investigated that the DES were physicochemical properties. |
| 저자 |
박준규, 김동곤, 남정표, 손동희, 김원석, 최창용, 장미경, 나재운
|
| 소속 |
순천대 |
| 키워드 |
DES; Rapamycin; biodegradable; stent
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| E-Mail |
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