| 학회 | 한국고분자학회 |
| 학술대회 | 2002년 가을 (10/11 ~ 10/12, 군산대학교) |
| 권호 | 27권 2호, p.185 |
| 발표분야 | 의료용 고분자 부문위원회 |
| 제목 | Preparation of microparticle as drug carrier by self-emulsifying |
| 초록 | The principal purpose of this study was the possibility to novel prepare microparticle as novel drug delivery system of microparticle. The size of prepared particle was in the range of 0.5～200㎛. Biodegradable poly(L-lactide-co- glycolide) (50:50 by mole ratio of lactide to glycolide, PLGA) particle was prepared by precipitation polymerization to study the possibility for release control and the characterization by SEM. This study was carried out by solvent evaporation and solvent extraction methods. The influences of several preparation parameters, such as surfactant types, molecular weights and concentrations of PLGA, etc., were observed in the particle size and morphology. This preparation method had advantages very simple processes and quick particle acquisition. Acknowledgment: This work was supported by KMOHW (Grant No.; HMP-98-G-2-051-B). |
| 저자 | 윤복영1, 서선아*2, 강복기*3, 정상영**, 강길선, 이해방**, 조선행** |
| 소속 | 1전북대, 2*전북대, 3**한국화학(연) |
| 키워드 | microparticle; self-emulsion; drug; carrier |
