초록 |
Fluorescent particles are of great interest in biotechnology for use as probes for bioimaging, diagnosis, and drug delivery in vivo and in vitro. For instance, fluorescent semiconductor quantum dots have been widely used because of their broad absorption, narrow photoluminescence, and high photostability. Fluorescent silica nanoparticles have been also developed with enhanced fluorescence and improved photobleaching for biological applications. Recently, carbon-based fluorescent materials, such as carbon nanoparticles and carbogenic quantum dots, have been investigated as alternative fluorescent nanomaterials. Here we report a new platform of fluorescent nanoparticles based on a fullerene nanoparticles. The newly-synthesized photoluminescent fullerene nanoparticles are simple to prepare and exhibit bright photoluminescence (PL), high photostability, easy penetration into live cells, and low cytotoxicity, all of which are essential properties for biological applications. |