| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
38권 2호 |
| 발표분야 |
기능성 고분자 (포스터발표만 진행) |
| 제목 |
Development of Material-independent Modification System with Poly(norepinephrine) for Promoting Cell Adhesion |
| 초록 |
Candidates for materials applied in the biomedical and tissue engineering fields are very limited due to the several reasons. One of them is promoting cell attachment by changing the surface chemistry of materials. Therefore, simple and purpose-fit method of surface modification has been explored. Having flexibility in substrates and giving room for post modification with biomolecules, polymer coating with catecholamine is especially being spotlighted. Inspired by mussel, versatile aqueous active surface modification system has been developed with catecholamine. In this study, the instant adhesion of cells was observed on the modified substrates by simply deep-coating method. Cytotoxicity assay and proliferation assay was also performed to ensure the condition of cells. Also, simple patterning system has been developed in macro-scale and micro-scale. Overall, we confirmed that the cell adhesion is boosted on modified substrates and additionally developed facile patterning system. |
| 저자 |
박민아1, 조선애2, 김은미1, 이해신3, 장재형1
|
| 소속 |
1연세대, 2카이스트, 3KAIST |
| 키워드 |
cell adhesion; patterning; catecholamine
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| E-Mail |
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