| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 가을 (10/20 ~ 10/22, 경주컨벤션센터) |
| 권호 |
46권 2호 |
| 발표분야 |
Virtual Lightning Session |
| 제목 |
Cell Patterning on a Poly(2-hydroxyethyl methacrylate) Film Based on Interfacial Dynamics |
| 초록 |
Thermal molecular motion in the outermost region of polymer films strongly impact on various material functions. Here we propose a novel concept for the two-dimensional (2D) regulation of chain dynamics at the water interface based on the introduction of silica nanoparticles (SiNP) into a polymer film, leading to the 2D-patterning of the fibroblast adhesion. A poly(2-hydroxyethyl methacrylate) (PHEMA) film was prepared on an SiNP line-patterned substrate. While X-ray photoelectron spectroscopic imaging confirmed that a whole outermost region of the film was fully covered with a single PHEMA component, atomic force microscopy-assisted force-distance curve measurements in water revealed that there were regions with different mechanical properties, that is, different interfacial dynamics, depending on the SiNP lines in the vicinity. On such a film, NIH3T3 cells showed heterogeneous adhesion and aggregates formation depending on the 2D-patterend interfacial dynamics. |
| 저자 |
Kento Kawabata, Masayasu Totani, Hisao Matsuno, Keiji Tanaka
|
| 소속 |
Kyushu Univ. |
| 키워드 |
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| E-Mail |
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