화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2010년 가을 (10/07 ~ 10/08, 대구 EXCO)
권호 35권 2호
발표분야 고분자 합성
제목 pH-Sensitive Hydrogel of carboxymethyl-β-Cyclodextrin incorporating Hydrophobically modified chitosan
초록 pH-sensitive hydrogels composed of carboxymethyl-β-Cyclodextrin(CM-β-CD) and Hydrophobically modified chitosan(HM chitosan) were prepared by substituting the hydroxyl groups of β-CD with carboxymethyl group and incorporating HM chitosan into CM-β-CD hydrogels. Epichlorohydrin (EPI) was used as a cross-linker and the molar ratio of EPI/ βCD was 15/1, 10/1 and 8/1. The number of carboxymethyl group per β-CD residue was determined by a titration method. The incorporation of the HM chitosan was qualitatively conformed by FT-IR spectroscopy and SEM. The swelling ratio and % release were higher in the acidic and alkali condition than neutral condition due to the electrostatic repulsion.
저자 김진철, 서승리, 서희진, 이미선
소속 강원대
키워드 pH-sensitive hydrogel; carboxymethyl-β-Cyclodextrin; HM chitosan
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