| 학회 |
한국고분자학회 |
| 학술대회 |
2017년 가을 (10/11 ~ 10/13, 제주컨벤션센터) |
| 권호 |
42권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Characterization and the hydrolytic degradation study of absorbable poly(p-dioxanone)(PPDO) monofilament suture [PDS™ II] |
| 초록 |
Characterization and the hydrolytic degradaton properties of absorbable poly(p-dioxanone) (PPDO) monofilament suture [PDS™ II] were studied by analyzing chemical structure, molecular weight, thermal properties, surface morphologies and pH changes. The results show that the relative number-average molecular weight of the sutures were about 50~55k g/mol[Standard material: PS]. The sutures seem to be treated at around 90℃ to improve physical properties. The temperature of maximum crystallization rate and the Activation energy for the sutures were about 40~50℃ and 80~100kJ/mol, respectively. The hydrolytic degradation properties of the sutures were strongly temperature dependent. At the beginning of the in vitro time, the tensile strength of the sutures decreased slowly but decreased considerably after a certain period of time, indication that the hydrolytic degradation proceeded in two steps. |
| 저자 |
이준희1, 고석연1, 고영주1, 민범찬1, 김혜림1, 김주관2
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| 소속 |
1(주)삼양바이오팜 의약바이오(연), 2(주)삼양바이오팜 MD공장 |
| 키워드 |
Absorbable poly(p-dioxanone)(PPDO) monofilament suture [PDS™ II]; Crystallization kinetic; Thermal decomposition; Activation energy; Hydrolytic degradation; In vitro; BSR(Breaking Strength Retention)
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| E-Mail |
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