| 학회 |
한국화학공학회 |
| 학술대회 |
2004년 가을 (10/29 ~ 10/30, 호서대학교(아산캠퍼스)) |
| 권호 |
10권 2호, p.1579 |
| 발표분야 |
생물화공 |
| 제목 |
Culture of human hair follicular cells and development of in vitro 3D hair growth model |
| 초록 |
The recent development of methods for culturing hair follicles in vitro has been proved to be an important tool to investigate many aspects of hair biology and drug screening on the hair growth. Hair follicles develop as a result of epithelial-mesenchymal interactions between epidermal keratinocytes and dermal papilla cells. We isolated and cultured some cell components of the human hair follicle, using explantation and enzymatic digestion method from human scalp skin, such as outer root sheath (ORS) cells, dermal papilla (DP) cells, dermal sheath (DS) cells, matrix cells and melanocytes. To induce hair morphogenesis in vitro the follicle cells were 3-D cultured simulating the normal skin structures. Moreover, to develop the organ culture model of hair follicle, we applied them in the dermal equivalent (DE) to expand hair growth period of the culturing hair follicles. |
| 저자 |
신연호1, 이두훈1, 서영권1, 유보영1, 송계용2, 김영진3, 양은경4, 박장서5, 장이섭6, 박정극1
|
| 소속 |
1동국대, 2중앙대, 3라이프코드, 4바이오랜드, 5두산, 6태평양 |
| 키워드 |
human hair follicle |
| E-Mail |
|
| 원문파일 |
초록 보기 |
