초록 |
Major challenges to the fabrication of microfluidic device using replica-molding and bonding methods include time consuming, multi-step, labor-intensive procedures, and especially high-cost involvement for sophisticated designs as 3D-micromixers. 3D printing has been considered as an alternative due to it is automated, assembly-free, economically beneficial. The study’s aim is demonstrating 3D-printed complicated Tesla structure microfluidic devices could enhance mixing performance of fluids within microchannel results in a high curcumin loading efficiency of polymeric nanoparticles. The nanoparticles were obtained by this device show potential properties to apply in drug delivery system like high homogeneity (PDI< 0.1) and small size (~100 nm). |