| 학회 |
한국화학공학회 |
| 학술대회 |
2014년 가을 (10/22 ~ 10/24, 대전 DCC) |
| 권호 |
20권 2호, p.2486 |
| 발표분야 |
신진연구자 심포지엄 |
| 제목 |
AuNP necklace array based electrochemical Field Effect Transistor (eFET) to measure the Membrane Potential of a cell |
| 초록 |
The cellular membrane potential is usually measured by inserting the micro-needles as a probe. This invasive measurement sometimes damages the cell during the process. Since the cellular reaction introduces the polarization inside the cell or near the cellular membrane, a few nanometer thick electrical double layer (EDL) on a device where the cells are deposited concomitantly changes. To measure this small EDL modulation caused by the cellular membrane potential modulation, electrochemical field effect transistors (eFET) employing low-dimensional nanomaterials, i.e., carbon nanotubes (CNT), silicon nanowires (SiNW), and graphene, have been proposed as the non-invasive measurements. Here, we will describe the eFET using ~10nm Au nanoparticle (NP) necklace array as a non-invasive biosensor platform. Due to high sensitivity and low capacitance of Au NPs, the eFET continuously measures subtle internal membrane potential modulation of green Algae during photosynthesis. |
| 저자 |
이승우1, 이은희2, Ravi. F. Saraf3
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| 소속 |
1Univ. of Nebraska-Lincoln / 한국과학기술(연), 2Univ. of Nebraska-Lincoln / 이화여자대, 3Univ. of Nebraska-Lincoln |
| 키워드 |
Electrochemical Field Effect Transistor; Gold Nanoparticle Necklace; Electrical Double Layer; Membrane Potential
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| E-Mail |
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| 원문파일 |
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