| 초록 |
Peptoids are a unique class of peptide mimics based on oligoglycine scaffolding. As a bioinspired material, the properties of peptoids lie in-between natural biopolymers and nonnatural synthetic polymers. Like biopolymers, they are information-rich polymers, offering precise control of main chain length, side chain functionality, and monomer sequence. The structural similarity to polypeptides has been responsible for the impressive diversity of biological activity observed for peptoids; however, non-natural N-substituents render them higher stability than that of natural counterpart (i.e., protease-stable). In this presentation I will introduce unique features of peptoids as a biomimetic material. Efforts to expand the boundary of the peptoid-based functional materials will also be presented. |
