| 학회 |
한국고분자학회 |
| 학술대회 |
2016년 봄 (04/06 ~ 04/08, 대전컨벤션센터) |
| 권호 |
41권 1호 |
| 발표분야 |
의료용 고분자 부문위원회 I |
| 제목 |
Mesoporous TiO2 with hydrogel as effective osteogenetic differentiation and cell localization assisting template |
| 초록 |
Tissue engineering is largely investigated academic field which involve multiple scientific area. Cell, biomolecules and scaffolds where cells are cultured are three key factors of tissue engineering. In this study, TiO2 substrate is used as culture scaffold with differentiation-promoting biomolecules immobilized on them for osteogenetic differentiation of hMSC. The covalent crosslink was formed in between TiO2 and growth factors for prolonged activity. The mesoporous structure assisted to increase immobilized protein amount as well as cell adhesion promotion. For obtain additional functionality other than just differentiation inducing scaffold, hydrogel technique was used to confine cell location on specific region. In vitro viability assays and imaging was proceeded and chemical characterization was utilized for analyze mesoporous TiO2 scaffold. |
| 저자 |
조강희, 고원건, 한상원, 민지홍, 유병용
|
| 소속 |
연세대 |
| 키워드 |
osteogenesis; cell localization; mesoporous TiO2
|
| E-Mail |
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