| 학회 |
한국재료학회 |
| 학술대회 |
2011년 봄 (05/26 ~ 05/27, 제주 휘닉스 아일랜드) |
| 권호 |
17권 1호 |
| 발표분야 |
D. Health and Biological Materials(생체 및 의용재료) |
| 제목 |
Fabrication and characterization of electrospun PLGA/Gelatin nanofiber tube for potential intestinal stent application |
| 초록 |
An electrospun Poly(lactice-co-glycolide acid) (PLGA) and Gelatin nanofiber tube was fabricated for potential intestinal stent application. Mechanical properties of tube were evaluated by tensile strength and burst strength tests. Physical and chemical properties were evaluated by contact angle measurement, swelling rates and porosity measurements. Biodegradability was investigated by immersion in simulated body fluid (SBF). Biocompatibility was investigated in vitro by cytotoxicity and proliferation studies by MTT assay, confocal microscopy and western blot using IEC-18 (Rat intestinal epithelial cell). After intestinal stent was implanted into rat bowel for periods from 7 to 10days, it was then analyzed using micro-computed tomography (Micro CT) and X-ray techniques. Futhermore, histological analysis was performed by hematoxylin-eosin (H&E) stain.
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| 저자 |
So-Ra Son1, Rose-Ann Franco2, Trinh-Quang Bao1, Sang-Ho Bae2, Young-Ki Min1, Byong-Taek Lee2
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| 소속 |
1Department of Biomedical Engineering and Materials, 2Soonchunhyang Univ. |
| 키워드 |
PLGA; Gelatin; Intestinal stent
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| E-Mail |
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