화학공학소재연구정보센터
학회 한국재료학회
학술대회 2009년 봄 (05/21 ~ 05/22, 무주리조트)
권호 15권 1호
발표분야 나노생체재료
제목 Fabrication of Fibrous Chitosan Mats Using Electro-spinning Process and Their Biocompatibility
초록 Fabrication of fibrous chitosan (CS) mats was investigated using electro-spinning process depending on different solvents at different concentrations. SEM morphology showed that CS fibrous mats were fabricated successfully by electrospinning. FT-IR (Fourier transform infrared spectroscopy) showed CS mat had successfully cross-linked. CS cross-linked fibrous mats were insoluble in water and could be washed perfectly to prevent water soluble bio-toxic agent. In vitro study, biocompatibility of fibrous mats not only before and after crosslinking mats but also including a washed mat were tested through MTT and SEM. MTT assay and SEM morphology showed that CS fibrous mat after washing showed high cell viability and low cytotoxicity compared to CS fibrous mat before washing.
저자 Thi Hiep Nguyen1, In-Seon Byun2, Ho-Yeon Song3, Byong-Taek Lee3
소속 1Department of Biomedical Engineering and Materials, 2College of Medicine, 3Soonchunhyang Univ.
키워드 Chitosan; cross-linking; electro-spinning; biocompatibility
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