| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 가을 (10/20 ~ 10/22, 경주컨벤션센터) |
| 권호 |
46권 2호 |
| 발표분야 |
기능성 고분자 |
| 제목 |
Trypsin Adsorption Behaviors of Surface-Imprinted Polymer Films Formed on Patterned Gold Surface Using Electrochemical Impedance Spectroscopy |
| 초록 |
In this study, electrochemical impedimetric biosensors were fabricated by electropolymerization of molecular imprinted materials on the patterned gold electrode for detecting trypsin (Trp). The gold patterns were grown among the hexagonal close-packed polystyrene colloid particles through chronoamperometry to fabricate hemispherical pore-patterned gold surface. Trypsin imprinted poly(o-phenylenediamine) films (Trp-MIP) were synthesized through CV under the optimized conditions. Adsorption properties such as limit of detection and selectivity of the Trp-MIP on the gold pore-patterned electrodes were investigated using electrochemical impedance spectroscopy and CV. In addition, the quantity of adsorption was evaluated by quartz crystal microbalance (QCM). The thin patterned Trp-MIP films confirmed a higher imprinting factor (IF = 3.51) in 48 μg/mL of Trp concentration than non-imprinted polymer (NIP) films and showed excellent selectivity. |
| 저자 |
최두영, 박진영
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| 소속 |
경북대 |
| 키워드 |
electrochemical biosensor; molecular imprinted polymer; electropolymerization; electrochemical impedance spectroscopy; colloidal lithograpy
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| E-Mail |
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