화학공학소재연구정보센터
학회 한국재료학회
학술대회 2010년 봄 (05/13 ~ 05/14, 삼척 팰리스 호텔)
권호 16권 1호
발표분야 D. Health and Biological Materials(생체 및 의용재료)
제목 Implantation of Small Artery Vessel from Blends PCL/PU with and without Anti-thrombus
초록 In this experiment, artificial blood vessel was fabricated from electro-spun PU/PCL. To assist with endothelial growth, PU/PCL surface was coated with the RGD peptide. To prevent a clot of blood, anti-thrombus agent was loaded to the fibrous mat and values were reflected through FT-IR data. In vitro study, SEM and MTT data showed that the component was of excellent biocompatibility and cell proliferation. In in vivo study, the artificial blood vessel was implanted in a dog’s artery. The results of the CT scan, ultrasound and H&E staining showed that artificial blood vessel was excellent for artery replacement applications.
저자 Nguyen Thi Hiep1, Seong Jin Lee2, Young-Ki Min3, Hun-Mo Yang4, Ho-Yeon Song5, Byong-Taek Lee3
소속 1Department of Biomedical Engineering and Materials, 2College of Medicine, 3Soonchunhyang Univ., 4Department of Thoracic and Cardiovascular Surgery, 5Chunan Hospital
키워드 PU; PCL; electrospinning; in vitro; in vivo
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