| 학회 |
한국고분자학회 |
| 학술대회 |
2011년 봄 (04/07 ~ 04/08, 대전컨벤션센터) |
| 권호 |
36권 1호 |
| 발표분야 |
International Symposium for Theranostic Macromolecules |
| 제목 |
Microfluidic Tissue Engineering: Towards In-Vitro Model of Vascularized Tissue Constructs |
| 초록 |
This presentation will describe recent results toward constructing vascularized tissue constructs using microfluidics technology. Despite increased understanding and knowledge of genomics, proteomics, and cell biology, attempts to develop new drugs often encounter difficulties due to limitations of conventional cell-based assays performed in 2D monolayer of cells. These cell-based assay models poorly resemble 3D tissues that are composed of blood vessels and multiple cell types. Our laboratory is developing a 3D tissue based drug screening platform that will be composed of connected blood vessels that will have similar flow characteristics as the normal or cancer tissues. We will describe various approaches that integrate fluid mechanics, microfluidics, and tissue engineering toward the goal of microfluidics based vascularized tissue construct for drug screening. |
| 저자 |
전누리 |
| 소속 |
서울대 |
| 키워드 |
microfluidics; tissue engineering; vascularized tissue construct; drug screening
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| E-Mail |
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