| 학회 |
한국화학공학회 |
| 학술대회 |
2006년 가을 (10/27 ~ 10/28, 고려대학교) |
| 권호 |
12권 2호, p.1806 |
| 발표분야 |
생물화공 |
| 제목 |
Peptide Nanotube-Modified Electrodes for an Electrochemical Immunosensor |
| 초록 |
Fabrication and notably improved performance of composite electrodes based on modified self-assembled peptide nanotubes is described. Peptide nanotubes extended tubular β-sheet-like structures were constructed by self-assembly of flat, ring-shaped cyclic peptides made up of alternation D- and L-amino acid residues. Fabricated nanotube structures were characterized by Fourier-transform infrared spectroscopy (FT-IR) and scanning electron microscopy (SEM). The peptide nanotubes were deposited onto the screen-printed carbon composite electrode as templates. The antibody against E.coli O157:H7 antibodies were attached onto the peptide nanotubes and the E.coli O157:H7 cells were attached onto the antibody-modified electrode using the antigen-antibody interaction. The results showed that the immobilization of antibodies and the binding of E. coli cells to the peptide nanotube modified electrode increased the electron-transfer resistance, which was directly measured with cyclic voltammetry (CV) in the presence of [Fe(CN)6]3-/4- as a redox probe. |
| 저자 |
조은찬, 최정우, 구기갑
|
| 소속 |
서강대 |
| 키워드 |
Peptide nanotube; immunosensor; E. coli O157:H7; cyclic voltammetry
|
| E-Mail |
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| 원문파일 |
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