| 학회 | 한국화학공학회 |
| 학술대회 | 2006년 봄 (04/20 ~ 04/21, 대구 인터불고 호텔) |
| 권호 | 12권 1호, p.782 |
| 발표분야 | 열역학 |
| 제목 | Measurement and Correlation of Drug Solubility in Supercritical Fluid |
| 초록 | Supercritical-fluid (SCF) technology has received much attention as an alternative solution for many difficult separation problems, mainly because of its enhanced transport properties and solubilizing power, and ease of solvent recovery. Recently experimental data for equilibrium solubility of solid including biochemical substances in supercritical fluid have measured. We measured drug solubility (Iodopropynyl butyl carbamate, IPBC) in supercritical carbon dioxide at 40, 50, 60 oC using variable volume view cell. IPBC is a biocide for pharmaceutical, cosmetic, food, and wood industries. We correlated IPBC solubility in supercritical carbon dioxide with cubic equation of state and lattice fluid equation of state. |
| 저자 | 유홍일, 신문삼, 신정인, 이윤우, 김화용 |
| 소속 | 서울대 |
| 키워드 | Supercritical Fluid; Drug Solubility; IPBC; Equation of state |
| 원문파일 | 초록 보기 |
