초록 |
Blood rheology becomes significantly important due to its close association with cardiovascular diseases and diabetic complications. In fact, blood is an amazing biofluid which fluidity is greater than those of any other suspensions. This is mainly due to red cell's unique characteristics such as deformability, aggregability, tank-treading motion, cell-migration, and Farhaeus-Lindqvist effect. If these characteristics, however, are degraded, there may occur serious circulatory disorders. We have developed innovative methods and devices to measure hemorheological properties at clinical environments. Our recent clinical study for diabetes showed that impairment of hemorheological properties in diabetic patients can be profoundly altered early, prior to the onset of diabetic complications and thus, the progressive impairmentof hemorheological property is strongly associated with the loss of microcirculatory organ functions in all diabetic patients. |