화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2013년 가을 (10/30 ~ 11/01, 대전컨벤션센터)
권호 17권 2호
발표분야 포스터-고분자
제목 Fabrication of biocompatible nanofibers using block copolymer(PCL/PCL-PEG)binding with collagen by electrospun for improve cellular infiltration tissue engineering
초록 Electrospun polymeric nanofibers have been extensively studied for biomedical materials because of their unique structures and relatively easy fabrication with biocompatible polymers. The amount of surface exposed amine groups increases as the blend ratio of block copolymer increases. Cell attachments on the nanofibers change according to the ratio of the block copolymer in the blend. So, we can assume that the PEG moiety plays a significant role in biocompatibility of nanofiber surfaces. Collagen was used as a grafting material on the composite nanofibers to enhance the cell adhesion because the collagen is a major constituent of connective tissue. We demonstrated that a simple route for fabricating nanofibers consist of block copolymer(PCL/PCL-PEG) binding with collagen by Electrospun. The resultant Nanofibers was characterized by scanning electron microscop(SEM), Energy Dispersive X-ray Spectroscopy(EDX), cyclic voltammetry(CV)
저자 이진우, 윤국로
소속 한남대
키워드 nanofiber; ultrasonication; block copolymer
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