| 초록 |
Melanin is a biopigment that exhibits multifunctionality, such as protection against ultraviolet radiation, radical scavenging, and thermal regulation through near-infrared light to heat conversion. Interestingly, the representative of artificial melanin, polydopamine, has received great attention as an adhesive used for surface coatings. However, the site-specific fabrication of polydopamine requires complicated procedures, extremely laborious and time consuming. Herein, we developed a simple site-specific fabrication method of polycatecholamine pigment by utilizing its adhesive property to horseradish peroxidase, a biocatalyst that initiates catechol oxidation. The pigment was successfully fabricated with high resolution and showed good biocompatibility. In addition, the pigment possessed a high photothermal conversion efficiency enough to induce local cancer cell killing on pigmented area. |
