| 학회 |
한국고분자학회 |
| 학술대회 |
2019년 가을 (10/09 ~ 10/11, 제주컨벤션센터) |
| 권호 |
44권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 II |
| 제목 |
Fiber-hydrogel scaffold with multi stimulation capability for cell differentiation |
| 초록 |
For the attempt to restore damaged cardiac tissue, application of tissue engineering onto the heart is researched widely. In tissue engineering, constructing environment similar to the real tissue is known to assist cell function, tissue formation and cell differentiation where two distinct nature of cardiac tissue are alignment and conductive properties. Here, we present scaffold with both physical alignment and electrical conductivity and moreover, with the capability of providing growth factors utilizing electrospinning and hydrogel system. Aligned fiber meshes were obtained with rotational collector in electrospinning setup followed by deposition of Au by metal evaporator. After that, sequential UV exposure on growth factor containing hydrogel precursor before and after mounting the prepared fiber sheet to combine fiber and hydrogel. Fabricated scaffold possessing multi stimulation capability was used for cell culture which promoted cardiac differentiation. |
| 저자 |
조강희, 윤병주, 홍혜진, 강성민, 최주환, 김혜원, 고원건
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| 소속 |
연세대 |
| 키워드 |
tissue engineering scaffold; multi stimulation; electrospinning
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| E-Mail |
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