화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2007년 봄 (04/12 ~ 04/13, 제주 ICC)
권호 32권 1호
발표분야 기능성 고분자 캡슐 공정 및 소재
제목 Synthesis and Characterization of PCL-based Amphiphilic Triblock Copolymers for Transdermal Penetration
초록 Biodegradable and amphiphilic triblock copolymers, used for the wall-materials for the encapsulation of skin active materials, were prepared by ring-opening polymerization of ε-caprolactone (ε-CL) and monomethoxy poly ethylene glycol (mPEG). The triblock copolymers were synthesized with varying the length of hydrophobic PCL moiety at the ratio of PEG to PCL, 1:0.5, 1:0.75, 1:1, and 1:1.25. The bulk properties of triblock copolymers were observed by using GPC, DSC, XRD, FT-IR, and Optical Microscopy. The characteristics of the PEG-PCL-PEG triblock copolymers as a wall material were confirmed by DLS and UV. (MOCIE, No. 10024160-2006-12)
저자 조희경1, 정인우1, 조진훈2, 김중현3
소속 1경북대, 2㈜아르떼르화장품기술(연), 3연세대
키워드 Amphiphilic; triblock copolymers; Encapsulation
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