| 학회 |
한국고분자학회 |
| 학술대회 |
2013년 가을 (10/11 ~ 10/12, 창원컨벤션센터) |
| 권호 |
38권 2호 |
| 발표분야 |
기능성 고분자 (포스터발표만 진행) |
| 제목 |
Study on microsphere for stimuli-responsive release systems |
| 초록 |
Alginate microspheres incorporating poly(hydroxyethyl acrylate-co-coumaryl acrylate-co-2-ethylhexyl acrylate) (P(HEA-CA-EHA)) were prepared using the water droplets of W/O emulsion as a template. The copolymer exhibited a lower critical solution temperature around 27 ℃ in distilled water. The microspheres were prepared by using O/W emulsion as a template and Ca2+ as a cross-linker for alginate. The resulting microspheres were subjected to a UV (365 nm) irradiation for the cross-linkage of P(HEA-CA-EHA). The microspheres were almost spherical and the size were less than 2 ㎛ in diameter. The irradiation of UV (254 nm) to the UV(365nm)-treated microsphere promoted the release of FITC-dextran, possibly due to the cleavage of the CA residue dimmers. However, the temperature change had little effect on the release degree in the range of 21℃ to 37℃. The thermally induced configurational change of the copolymer seemed to be restricted due to the photo dimmerization of the AC residues. |
| 저자 |
이주협, 김진철, 조창현
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| 소속 |
강원대 |
| 키워드 |
Alginate; P(HEA-CA-EHA); Emulsion; Microsphere; Release
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| E-Mail |
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