화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2009년 가을 (10/15 ~ 10/16, 서울산업대학교 내 서울테크노파크)
권호 13권 2호
발표분야 기능성 화장품 소재 및 경피흡수 기술개발
제목 Iontophoretic Transdermal Drug Delivery of Therapeutic Drugs
초록 Iontophoresis is the process of introducing ionic drugs into the body for therapeutic purposes. Iontophoresis of ionized drugs provided a 10~50 fold increase in penetration over topical application. The aim of this work was to study the factors affecting transdermal iontophoretic delivery preparations of peptide drug and bisphosphonates for treatment of osteoporosis. Iontophoretic delivery was optimized by evaluating the effect of current density, pH of the drug solution, penetration enhancers, time of current application and donor concentration.
저자 길영식1, 정상영1, 정석현2, 조선행2, 신병철2, 오승열3
소속 1한국콜마(주), 2한국화학(연), 3숙명여자대
키워드 Iontophoresis; transdermal drug delivery; osteoporosis
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