| 학회 |
한국고분자학회 |
| 학술대회 |
2021년 가을 (10/20 ~ 10/22, 경주컨벤션센터) |
| 권호 |
46권 2호 |
| 발표분야 |
의료용 고분자 부문위원회 Ⅰ,Ⅱ |
| 제목 |
3D printing of skin-mimetic construct for tissue engineering application |
| 초록 |
In recent years, several 3D bioprinting techniques have emerged to synthesis 3D tissue analogue. Accordingly, many are focusing into development of novel bioinks that can mimic the natural extracellular matrix (ECM) with cytocompatibility and biofunctionality. Herein, we developed gelatin methacryloyl/hyaluronic acid methacryloyl (GelMA/HAMA)bioink that features rapid and cytocompatible crosslinking process by UV-radiated curing. The 3D printability of GelMA/HAMA hydrogel were optimized and the 3D printed construct showed high structural fidelity. Furthermore, dermis-epidermis double layer was implemented exhibiting high cytocompatibility both on human keratinocytes and dermal fibroblasts. In conclusion, it is suggested that GelMA/HAMA hydrogel can be promising candidates as bioink for skin tissue 3D printing. |
| 저자 |
강문성1, 이석현1, 장희정1, 조효정1, 이종호2, 김춘태3, 한동욱1
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| 소속 |
1부산대, 2다안코리아, 3BIO-IT Foundry Technology Institute |
| 키워드 |
3D printing; skin; tissue engineering
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| E-Mail |
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