| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO)) |
| 권호 |
25권 1호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Enhanced Osteoblast Behaviors on PLCL/Collagen Nanofibrous Matrices Incorporated with MXene Nanosheets |
| 초록 |
MXene is one of the most emerging two-dimensional (2D) nanomaterials, has drawn increasing attention due to its unique physicochemical properties. Herein, the osteogenic potential of MXene nanosheets was explored and then they were fabricated into electrospun poly(L-lactide-co- ε-caprolactone)/collagen/MXene (PLCL/Col/MXene) nanofiber matrices to further investigate their synergistic effect for bone tissue engineering (BTE) scaffolds. It was found that PLCL/Col/MXene nanofiber matrices were shown to promote spontaneous osteogenic differentiation of MC3T3-E1 preosteoblasts without hampering cell growth. These results indicate that the PLCL/Col/MXene nanofiber matrices possess excellent biocompatibility and effective osteogenic activity. In conclusion, it is suggested that the PLCL/Col/MXene nanofiber matrices can be promising candidates as novel scaffolds for BTE. |
| 저자 |
이석현1, 강문성1, 이지은1, 조효정1, 이종호2, 홍석원1, 한동욱1
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| 소속 |
1부산대, 2다안 코리아 |
| 키워드 |
MXene; Electrospinning; Nanofiber matrix; Bone tissue engineering; Osteogenesis
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| E-Mail |
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