화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2022년 봄 (05/11 ~ 05/13, 제주국제컨벤션센터(ICC JEJU))
권호 26권 1호
발표분야 포스터-고분자
제목 Thermo-responsive metal coated PVP microneedle patch prepared by radiationcrosslinking​
초록 Polyvinylpyrrolidone (PVP)-based hydrogel-type microneedle patch was prepared using radiation crosslinking technique. The back side of the PVP based microneedle patch were coated with gold or silver. To demonstrate effective drug release by thermal conductivity using Near-Infrared-Light (NIR), each sample was irradiated with laser light. When ~ 40 ℃ heat were applied, the drug-release efficiency of the Au- and Ag-coated PVP based microneedle patches improved about 5 times compared to a flat PVP patch at room temperature



저자 박종석, 이장건, 오용현, 정성린, 박용대, 전준표, 임윤묵
소속 한국원자력(연)
키워드 PVP hydrogel; Microneedle array; Drug delivery; Thermal stimulus; Radiation crosslinking
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