| 초록 |
Cell patterning is increasingly important for a wide variety of biomedical applications including cell-based biosensors, lab-on-a-chip, microfluidics, and tissue engineering. Recently, cell patterning has emerged as a valuable tool for the drug screening and the monitoring of environmental and chemical products in a cellular level. In this study, cell patterning with both adherent and nonadherent cells were created by piezoelectric inkjet printing with a biocompatible anchor of membrane (BAM), which consists of an oleyl group and a poly(ethylene glycol) (PEG). Both type of cells were strongly anchored and patterned on the BAM-modified substrate by interactions between the cell membrane and an oleyl group of BAM. This approach could be an effective technique to control the attachment of nonadherent cells as well as adherent cells, leading to periodically ordered, living cell arrays. |
