| 학회 | 한국화학공학회 |
| 학술대회 | 2005년 가을 (10/21 ~ 10/22, 인하대학교) |
| 권호 | 11권 2호, p.1811 |
| 발표분야 | 공정시스템 |
| 제목 | A web-based simulation environment for metabolic control analysis of cellular network systems |
| 초록 | We developed a web-based environment for elucidating the parameters responsible for the control of flux, which is one of the most important goals of metabolic engineering for new knowledge discovery. Metabolic control analysis aims to characterize the sensitivity of metabolic responses with respect to changes in enzyme activities or parameters at the steady state. It is designed as a user-friendly web interface, allowing users to efficiently analysis and simulates biological reaction network models, thereby facilitating kinetic modeling and simulation of biological systems under development. This makes it suitable for scientists and students with limited computer experience. ACKNOWLEDGMENTS: This work was supported by the Korean Systems Biology Research Program of the Ministry of Science and Technology and by the BK21 project. Further supports from LG Chemicals Chair Professorship and IBM-SUR program are greatly appreciated. |
| 저자 | 윤좌문1, 이동엽2, 오영균1, 이상엽3, 박선원1 |
| 소속 | 1한국과학기술원 생명화학공학과 / 초미세화학공정센터, 2한국과학기술원 Bioinformatics Research Center, 3한국과학기술원 생명화학공학과 / 한국과학기술원 Bioinformatics Research Center |
| 키워드 | Dynamic simulation; web; Metabolic Control Analysis; Internet; Systems biology |
| 원문파일 | 초록 보기 |
