화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2006년 봄 (05/12 ~ 05/13, 전북대학교)
권호 10권 1호
발표분야 나노기술
제목 Preparation and release behavior of ursolic acid–loaded liposomes
초록 The liposomal delivery system can be applied to administrate the drug and other bioactive agent. There are currently a number of commercially available liposomal formulations. In this research, the nano-sized liposomes were prepared using the phosphatidyl choline. The size and size distribution and electric charge were investigated in the encapsulated liposome. To investigate the encapsulation into the liposome, the ursolic acid was used as a model agent. Because several pharmacological effects, such as, anti-tumor, hepatoprotective, anti-inflammatory, anti-ulcer, antimicrobial, anti-hyperlipidemic and antiviral, can be attributed to ursolic acid. In particular, its anti-inflammatory, anti-tumor, and antimicrobial properties are pertinent to the cosmetic industry.
저자 오승룡, 이상봉, 조계민, 심진기
소속 한국생산기술(연)
키워드 Liposome; Phosphatidyl choline; Ursolic acid; Encapsulation efficiency; Release
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