화학공학소재연구정보센터
학회 한국고분자학회
학술대회 2003년 가을 (10/10 ~ 10/11, 부경대학교)
권호 28권 2호, p.391
발표분야 의료용 고분자 부문위원회
제목 Surface modificatin of segmented polyetherurethane for cardiovascular graft (I)
초록 Linear, segmented polyetherurethane (SPEU) is known as a copolymer with a distribution of hard- and soft-segment blocks. There are various ranges of chemical, physical and biocompatible properties depending on the portion of the hard and soft phases. In addition, the SPEU is also considered as one of the most tissue and blood compatible materials accepted as vascular graft replacements today. In this study, we attempted to apply the semi-microporous PTMEG 1000-based SPEU surface with human microvascular endothelial cells (HMVECs), and examined HMVECs proliferation on the surfaces. In addition, the surface modification of the SPEU with collagen, which increases cell attachment, was examined. The tensile strength test was carried out to check the mechanical property. The compliance was estimated by using Young's Modulus. Cell attachment and proliferation of HMVEC seeded SPEU was determined by DNA quantities.
저자 조은희1, 양영일1, 김정구2
소속 1인제대, 2백인제기념(연)
키워드 segmented polyetherurethane; semi-microporous surfaces; compliance; endothelial cell; cardiovascular graft
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