| 학회 |
한국공업화학회 |
| 학술대회 |
2017년 가을 (11/08 ~ 11/10, 부산 벡스코(BEXCO)) |
| 권호 |
21권 2호 |
| 발표분야 |
우수논문(구두)_박사과정 |
| 제목 |
Multiplexed digital assay in a three-dimensional paper-based microfluidic analytical device |
| 초록 |
Here, we demonstrate 3-dimensional (3D) paper-based microfluidic channels to control 3D flow for automatic multiplexed digital assay. The 3D channels were fabricated by double-sided printing and lamination process. We print and laminate asymmetrical and symmetrical wax patterns on the paper to form 3D channels, and to create 3D fluidic flow for multiplexed digital assay. The 3D channels contains lateral and vertical channel. The asymmetrical wax-patterns form lateral and vertical channels. The symmetrical wax-patterns form vertical channels when the melted wax make contact with each other. We injected red dye into inlet of channels to track 3D capillary flow in the 3D channel. We conformed that the 3D fluid flow in a thickness of a paper. Based on this concept, we created 3D devices for automatic digital assay to detect glucose and albumin. Therefore, we expect that this method could be an instrument-free and multiplexed assay format for use in developing countries. |
| 저자 |
정성근, 진시형, 이병진, 심규락, 김동영, 강소립, 이창수
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| 소속 |
충남대 |
| 키워드 |
paper-based; digital assay; diagnosis
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| E-Mail |
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