화학공학소재연구정보센터
학회 한국공업화학회
학술대회 2021년 봄 (05/12 ~ 05/14, 부산 벡스코(BEXCO))
권호 25권 1호
발표분야 포스터-생체재료
제목 Ultra-fast and universal detection of Gram-negative bacteria in complex samples based on colistin derivatives
초록 The infectious bacteria has recently been recognized as a serious disease that becomes resistant to antibiotics. Therefore, the rapid and differential detection of bacterial species would minimize the overuse of antibiotics and the spread of antibiotics resistance. Herein, we introduce a method utilizing a fluorescent derivative of colistin (COL-FL) that directly label on outer-membrane of Gram-negative bacteria. Using the COL-FL assay, we achieved the differential fluorescence assay of various Gram-negative bacteria within 10 min, which could be subsequently detected via spectrofluorometry and microscopy.  
저자 류제성, 정현정
소속 한국과학기술원
키워드 antibiotic; Gram-negative; diagnosis
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