| 학회 |
한국공업화학회 |
| 학술대회 |
2021년 가을 (11/03 ~ 11/05, 대구 엑스코(EXCO)) |
| 권호 |
25권 2호 |
| 발표분야 |
포스터-생체재료 |
| 제목 |
Elimination of Unconverted Double Bonds in the Polymer Networks of Microparticles Synthesized via Flow Lithography |
| 초록 |
Flow lithography (FL), a versatile technique used to synthesize anisotropic multifunctional microparticles, has attracted substantial interest, given that the resulting particles with complex geometries and multilayered biochemical functionalities can be used in a wide variety of applications. However, after this process, there are double bonds remaining from the cross-linkable groups of monomers which can affect the particles’ biochemical properties. In this research, we verify that the microparticles produced by FL contain a significant number of unreacted acrylate double bonds (UADBs), regardless of the various synthetic conditions. We present an effective way to eliminate a substantial amount of UADBs after synthesis by linking biochemically inert poly(ethylene glycol) based on click chemistry. We validate that the hydrogel particles free of UCDBs show chemically inert, much higher biocompatibility compared with those of untreated controls. |
| 저자 |
배수현1, 문현준1, 구민희2, 노윤호1, 이현지1, 양재문2, 봉기완1
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| 소속 |
1고려대, 2연세대 |
| 키워드 |
Unreacted acrylate double bond; Flow lithography; Hydrogel microparticle
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| E-Mail |
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