| 초록 |
New quaternary ammonium chlorides, [alkyldimethyl-[5-(2-phenylthiazol-4-yl)1,3,4-oxadiazol-2-ylmethyl]quaternary ammonium chloride (ADOQACs : 6)] were obtained in high yield by the reaction of compound 5 with N,N-dimethylalkyl amines in isopropyl alcohol. The structure and physical properties of these compounds were investigated and some surfactant properties of them were measured. The surface tension and the minimal inhibitory concentration(MIC) of compound 6 were found to be influenced by the alkyl group, specially compound 6c and 6d exhibited high bacterial activity and good surface activity.
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