| 학회 |
한국고분자학회 |
| 학술대회 |
2015년 봄 (04/08 ~ 04/10, 대전컨벤션센터) |
| 권호 |
40권 1호 |
| 발표분야 |
고분자합성 |
| 제목 |
Phospholipid-b-Poly(Amino Acid)s Synthesized by Ring Opening Polymerization and its Self-assembling Behavior |
| 초록 |
Herein we report on the synthesis of various poly(amino acid)s with phosphatidylethanolamine (PE) as a initiator. PE was extracted from soybean lecithin that was successfully purified by flash chromatography. The series of phospholipid-b-poly(amino acid)s were synthesized by the ring opening polymerization of the N-carboxy anhydrides (NCA) of various amino acids. The synthetic approach yields a series of polymers with different amino acid monomer but with similar molecular weight of around 2000. PE-b-poly(amino acid)s based amphiphilic lipid micelles have been fabricated by self-assembly process using solubility difference toward solvents. Nuclear magnetic resonance spectroscopic techniques (NMR) were used to characterize each product. The morphologies and diameters of micelles were observed by transmission electron microscope (TEM). |
| 저자 |
박희주1, 김일2
|
| 소속 |
1BK21플러스 동남권 화학신기술 창의인재양성 사업단, 2부산대 |
| 키워드 |
Phospholipid-b-poly(amino acid)s; N-carboxy anhydrides; Ring-opening polymerization; Amphiphilic lipid layer micelle; Self-assembly
|
| E-Mail |
|
