| 학회 | 한국재료학회 |
| 학술대회 | 2016년 봄 (05/18 ~ 05/20, 여수 디오션리조트 ) |
| 권호 | 22권 1호 |
| 발표분야 | D. 구조 재료 분과 |
| 제목 | Metallic 3D printer for the optimal design of orthopedic implant |
| 초록 | There has been increasing research interest in the metallic three dimensional (3D) scaffolds for the filling of major damage in the skeletal structure. Motives influencing the design of scaffolds are often based upon mimicking one or more properties of natural bone which is the intended tissue to be repaired. Recently, additive manufacturing (AM) technologies have gained popularity for 3D scaffold fabrication, especially for bone tissue engineering due to their reproducibility, reliability and capability to design precise porous architecture. These technologies have great potential to overcome the limitation of conventional manual-based fabrication techniques. In this presentation, new cylindrical bone implants containing elongated pores interconnected as open pores were fabricated by an electron beam melting (EBM) and new bone in the elongated pore of implant were analyzed by preferential orientation of biological apatite (BAp) c-axis. BAp c-axis orientation was reflected intrinsic property of bone tissue (bone quality), and it was assessed by microbeam X-ray diffractometer (μXRD) technique. These implants could be grafted into the forearm ulna of a 3 month-old male New Zealand White rabbits. The analysis of bone quantity and bone quality carried out in the regenerated bone using the micro CT and micro XRD. Bone mass and preferential degree of biological apatite c-axis as a bone quality parameter decreased with the distance from the edge of implant along the longitudinal bone axis because of a stress shielding effect. However, clear interconnection of new bone appeared through the implant with elongated pores parallel to the bone axis, while the defected portion was not recovered with new bone without the new implant. This research was supported by Basic Science Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Education(2009-0093814) |
| 저자 | 이지욱1, 이병수2, 이강식3, 김유찬4, 석현광4 |
| 소속 | 1국민대, 2한국생산기술(연), 3아산병원 의공학센터, 4한국과학기술(연) |
| 키워드 | Additive manufacturing; Implant; Bone regeneration |
