| 학회 |
한국고분자학회 |
| 학술대회 |
2010년 봄 (04/08 ~ 04/09, 대전컨벤션센터) |
| 권호 |
35권 1호 |
| 발표분야 |
고분자 합성 |
| 제목 |
Synthesis and characterization of poly (2-hydroxy ethyl methacrylate)-b-poly (L-histidine) diblock co-polymers |
| 초록 |
We have used the combination of atom transfer radical polymerization (ATRP) and ring opening metathesis polymerization (RMOP) to synthesize a series of poly [2-hydroxy ethyl methacrylate-bL-histidine] (PHEMA-b-PHIST) block co-polymers. 2-hydroxyethyl methacrylate (HEMA) was polymerized in a controlled way by ATRP without the use of hydroxyl protecting groups. Fast growth of the poly (HEMA) block was achieved with a CuBr/bipyridine system. The terminal halogen atom of the poly (HEMA) was changed to primary amine function, followed by silylation which serves as a macro initiator for the silazane mediated controlled polymerization of Benzyl-N-carboxy-L-histidine anhydride (HIS-NCA) via RMOP. The FT-IR and NMR analysis confirmed the complete terminal functionalization of the macro initiator. SEC measurements indicated complete attachment of the second block resulting in narrow polydispersity. (Mn = 5500-10000). |
| 저자 |
렌지스1, 하창식2, 김일1
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| 소속 |
1부산대, 2합성고분자 생물접합 하이브리드 재료 사업단 |
| 키워드 |
Atom transfer radical polymerization (ATRP); Ring opening metathesis polymerization (RMOP); 2-Hydroxyethyl methacrylate (HEMA); Benzyl-N-carboxy-L-Histidine anhydride (HIS-NCA)
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| E-Mail |
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